解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::The aim of this study was to investigate the concurrent validity of the French language version of the Calgary Depression Scale for Schizophrenics (CDSS). Ninety-five schizophrenic patients meeting the DSM-III-R criteria were enrolled in the study. The depressive symptoms were evaluated using the Calgary Depression Sc...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(99)00075-0
更新日期:2000-05-01 00:00:00
abstract:BACKGROUND:Many studies have demonstrated that major depression is related to an activation of the inflammatory response system (IRS) with an increased production of proinflammatory cytokines. It has been shown that tricyclic antidepressants and serotonin reuptake inhibitors suppress the activation of the IRS in depres...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(99)00076-2
更新日期:2000-04-01 00:00:00
abstract:BACKGROUND:Concerns have been expressed about the reliability and validity of the DSM-IV criteria for schizoaffective disorder, but no systematic study has been published up to now. METHODS:The Cohen's kappa for the individual items of the DSM-IV definition of schizoaffective disorder, manic episode and major depressi...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(99)00059-2
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:Most of the data on lifetime psychiatric comorbidity in combat-related posttraumatic stress disorder (CR-PTSD) were collected in help-seeking patients. METHODS:In the present study we used the Schedule for Affective Disorder and Schizophrenia-Lifetime Version to examine a relatively large sample (n=80) of I...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(99)00090-7
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:Sudarshan Kriya Yoga (SKY) is a procedure that involves essentially rhythmic hyperventilation at different rates of breathing. The antidepressant efficacy of SKY was demonstrated in dysthymia in a prospective, open clinical trial. This study compared the relative antidepressant efficacy of SKY in melancholia...
journal_title:Journal of affective disorders
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0165-0327(99)00079-8
更新日期:2000-01-01 00:00:00
abstract:OBJECTIVE:This paper examined sex differences in the short-term course of depression and assessed the impact of possibly outcome-affecting factors, including sex-specific recall artefacts and demographic and clinical characteristics. METHODS:A cohort of 179 unipolar depressed inpatients was followed up 1 (T1) and 7 mo...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(99)00035-x
更新日期:1999-12-01 00:00:00
abstract:OBJECTIVE:To examine for a relationship between childhood trauma and depression in alcoholics. METHODS:Euthymic depressed alcoholics (N = 23) were compared with never depressed alcoholics (N = 20) for their scores on the Childhood Trauma Questionnaire (CTQ). Subjects also completed the Hostility and Direction of Hosti...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(99)00044-0
更新日期:1999-12-01 00:00:00
abstract:BACKGROUND:One explanation for the high co-occurrence between bipolar and substance use disorders is that substance abuse may precipitate affective symptoms in patients who otherwise may have not had the genetic risk for developing an affective illness. Previous studies comparing familial rates of affective illness bet...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(99)00029-4
更新日期:1999-11-01 00:00:00
abstract:BACKGROUND:This study investigates the rate of cerebral blood flow (rCBF) in Arab patients wth depression. METHODS:Forty-four patients with DSM-III-R major depressive disorders were studied at rest using single photon emission computerized tomography (SPECT) with 99m Tc-HMPAO in comparison with 20 normal controls. All...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(98)00209-2
更新日期:1999-10-01 00:00:00
abstract:BACKGROUND:Though the social functioning of most depressed outpatients improves with effective treatment, a subgroup may remain impaired after recovering from depression. The purpose of this study was to identify predictors of residual social impairment among patients who recovered from depression. METHODS:These data ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(98)00200-6
更新日期:1999-10-01 00:00:00
abstract:BACKGROUND:This study assesses depression among primary care patients, the relationship between depression and functioning, and how frequently depressed individuals receive mental health treatment. METHODS:Two hundred and thirteen participants completed a diagnostic interview and measures of functional impairment and ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(98)00191-8
更新日期:1999-09-01 00:00:00
abstract:OBJECTIVE:To evaluate the efficacy of gabapentin as an adjunctive treatment for bipolar disorder in both depressed and manic phases. METHOD:Thirty seven patients with bipolar type I or II with or without a rapid cycling course were openly treated with gabapentin added to current treatment for up to six months. Mood sy...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(98)00192-x
更新日期:1999-09-01 00:00:00
abstract:BACKGROUND:The results of multivariate analyses to identify potential predictors of response to fluoxetine or placebo separately in 96 child and adolescent outpatients with major depressive disorder from a recent controlled trial are presented. METHODS:A variety of clinical, demographic and laboratory factors were exa...
journal_title:Journal of affective disorders
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0165-0327(98)00205-5
更新日期:1999-08-01 00:00:00
abstract:BACKGROUND:The number of ECT treatments given each year is a topic of interest for psychiatrists, users and politicians, but there are major methodological problems in reported studies of rates of ECT use in the British Isles. The aim was to establish whether or not the use of ECT had fallen between 1992 and 1997. MET...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(98)00144-x
更新日期:1999-07-01 00:00:00
abstract:BACKGROUND:Results from short-term treatment studies have demonstrated the efficacy of antidepressant medications for outpatients with early-onset chronic depression. However, scant data exists regarding the long-term outcome of these patients treated for this disorder. METHODS:The author conducted a one-year naturali...
journal_title:Journal of affective disorders
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0165-0327(98)00040-8
更新日期:1999-07-01 00:00:00
abstract::Epidemiological surveys demonstrate that unipolar depression is more common in females than in males. Gender-specific cultural and social factors may contribute to the female preponderance. This study explores this possibility in a cross-cultural sample of general-practice patients systematically recruited in the WHO ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(98)00131-1
更新日期:1999-06-01 00:00:00
abstract:BACKGROUND:Epidemiologic surveys consistently document high rates of untreated depression, yet why this unmet need exists is only partially understood. METHODS:We compared untreated depressed, treated depressed and "healthy" subjects on sociodemographic characteristics, need for treatment, and help-seeking attitudes u...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(98)00116-5
更新日期:1999-05-01 00:00:00
abstract:BACKGROUND:A previous study which compared euthymic Israeli bipolars in a public hospital clinic to US normative data suggested that low Persistence scores on the Tridimensional Personality Questionnaire (TPQ) may be a temperament marker for manic-depressive illness. The current study attempts to replicate that finding...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(98)00075-5
更新日期:1999-04-01 00:00:00
abstract:BACKGROUND:To devise and evaluate the retention of a new brief training package for non-psychiatrically trained multidisciplinary staff to assess suicide risk and manage suicidal patients, including referral of patients at significant risk to psychiatric staff. METHOD:8 h of interview skills training, using role play ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(98)00080-9
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND:Previous studies have shown that depression is more prevalent in vascular dementia than Alzheimer's disease (AD). Subjects for these studies were either psychiatry or neurology patients, raising the issue of whether factors leading to treatment might have introduced sampling bias. METHODS:Data for the prese...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(98)00070-6
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND:To examine neuroticism as a possible determinant of depression in alcoholics. METHOD:24 euthymic depressed alcoholics and 18 never-depressed alcoholic controls completed the Eysenck Personality Questionnaire. RESULT:Euthymic depressed alcoholics had significantly higher neuroticism scores than alcoholic co...
journal_title:Journal of affective disorders
pub_type: 临床试验,杂志文章
doi:10.1016/s0165-0327(98)00071-8
更新日期:1999-01-01 00:00:00
abstract::Tricyclic antidepressants have multiple sites of pharmacological actions which are responsible for their tolerability and toxicological problems as well as their efficacy. That fact has prompted the search for antidepressants with fewer sites of action. That search resulted in the serotonin selective reuptake inhibito...
journal_title:Journal of affective disorders
pub_type: 杂志文章,评审
doi:10.1016/s0165-0327(98)00222-5
更新日期:1998-12-01 00:00:00
abstract::The frequency of occurrence of prepubertal mania is contingent on how much adherence to episodic disorder with separate periods of mania and depression is required. While manic symptoms superimposed on other psychiatric disorders is not uncommon, non-comorbid bipolar disorder is rare. A number of developmental, phenom...
journal_title:Journal of affective disorders
pub_type: 杂志文章,评审
doi:10.1016/s0165-0327(98)00179-7
更新日期:1998-11-01 00:00:00
abstract:BACKGROUND:Personality assessment may allow reliable measurement of risk of mood disorders. METHODS:A group of adults (804) representative of the general population were assessed by questionnaire. Personality types were measured by the Temperament and Character Inventory (TCI). RESULTS:Specific TCI configurations def...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(98)00153-0
更新日期:1998-10-01 00:00:00
abstract:BACKGROUND:Although recent studies have shown high rates of current and lifetime depression in HIV-infected patients, there is little systematic data on the occurrence of bipolarity in these patients. METHOD:We compared 46 HIV patients with index major depressive episode (MDE) to an equal number of age- and sex-matche...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(98)00111-6
更新日期:1998-09-01 00:00:00
abstract:BACKGROUND:Robust predictors of long-term outcome in bipolar affective disorder would have substantial importance to both clinicians and researchers. Such predictors are not available, however, perhaps because of the limitations of previous efforts to find them. METHODS:In this study, 113 patients with bipolar affecti...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(98)00043-3
更新日期:1998-09-01 00:00:00
abstract:BACKGROUND:Because secular trends in seasonality of different types of suicides has not been studied before, we utilized a novel statistical method to evaluate this phenomenon by using national Finnish suicide statistics during 1980-95. METHODS:Rates were analyzed with ordinary linear regression analysis. Secular tren...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(98)00031-7
更新日期:1998-07-01 00:00:00
abstract:BACKGROUND:This study compares antidepressant efficacy and tolerability of citalopram given either orally or as a slow drop infusion. METHODS:Citalopram (40 mg/day) was administered double-blindly as tablets or slow-drop infusion during the first 10 days and then open, orally, up to treatment Day 42. RESULTS:In 60 mo...
journal_title:Journal of affective disorders
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0165-0327(98)00024-x
更新日期:1998-06-01 00:00:00
abstract:BACKGROUND:Suicide attempts have been associated to both Major Depression and Borderline Personality Disorder. This report hypothesized that there would be significant clinical differences between psychiatric outpatients with Major Depression, Major Depression with a history of a suicide attempt (but low Borderline tra...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(98)00009-3
更新日期:1998-05-01 00:00:00
abstract:BACKGROUND:The study's aim was to examine insight in mood disorders in relation to type of mood episode, psychotic state, and insight change over the episode. METHODS:Fifty four patients with a manic or major depressive episode were interviewed for insight assessment at admission and discharge. RESULTS:At admission, ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(97)00198-5
更新日期:1998-04-01 00:00:00
abstract::A clinical study was conducted to examine the effects of depression on cardiac autonomic control. Cardiac autonomic control was measured in 26 nonmedicated patients (19 females) suffering from Major Depression, melancholic type, and in 26 age- and sex-matched normal controls. We measured heart rate and high frequency ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(97)00164-x
更新日期:1998-03-01 00:00:00
abstract:OBJECTIVE:Because of the relationship between childhood behavior disorders and adult substance abuse, we hypothesized that substance abusing adult bipolars were more likely to have had behavior disorders as children than nonabusing bipolar adults. METHODS:Conduct disorder (CD) symptoms in 132 bipolar adults were compa...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(97)00176-6
更新日期:1998-03-01 00:00:00
abstract::To examine for sex differences in anticipated and actual impact of pleasant and unpleasant life events in a non-clinical group, a cohort of 164 subjects was initially assessed in 1978 in their last year of teacher training. They were asked to participate in the life events study in 1979, and 97 subjects complied, prov...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(97)00138-9
更新日期:1998-02-01 00:00:00
abstract::We retrospectively investigated the relationship between major depression and silent cerebral infarction (SCI) over a 3-year period in 64 patients older than 50 years of age with unipolar depression. All patients underwent magnetic resonance imaging (MRI) at their first admission for depression and were classified int...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(97)00148-1
更新日期:1998-01-01 00:00:00
abstract::Using desmethylimipramine (DMI) defined and Na+ dependent [3H]imipramine binding, we have examined both 5-HT uptake sites and sites unrelated to 5-HT uptake, in frontal cortex, putamen and substantia nigra of suicides with a firm retrospective diagnosis of depression and matched controls. No differences were seen betw...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(97)00126-2
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND:Previous studies reporting cortisol hyposecretion in chronic fatigue syndrome may have been confounded by venepuncture, fasting and hospitalisation. METHODS:Morning and evening salivary cortisol were obtained on consecutive days in the first 3 days of the menstrual cycle and compared in three samples of wom...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(97)00134-1
更新日期:1998-01-01 00:00:00
abstract::The authors compared the presentation and course of major depression in male geriatric inpatients with and without a diagnosis of dementia. Of 326 consecutive admissions to an inpatient geropsychiatry unit, 22 (7%) had a diagnosis of major depression without dementia, 35 (11%) had major depression with dementia. Both ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(97)01430-4
更新日期:1997-12-01 00:00:00
abstract::Two hundred thirty-seven (237) manic patients diagnosed by DSM-III-R criteria as either purely manic (204) or mixed bipolar (33) were reviewed for analysis of the diagnostic performance of the DSM-III-R criteria required to diagnose the mixed bipolar state. We calculated the sensitivity, specificity, positive predicti...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(97)00084-0
更新日期:1997-10-01 00:00:00
abstract::Several concepts of minor depression in the sense of acute but less severe symptomatology than major depression have been proposed in the literature, but currently none of them is generally accepted. For the treatment of these conditions, only few recommendations based on empirical data are available. We conducted a r...
journal_title:Journal of affective disorders
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/s0165-0327(97)00072-4
更新日期:1997-09-01 00:00:00
abstract::Data presented during the 1996 CINP President's Workshop supported the conclusion that unipolar major depressive disorder (MDD) is a pleomorphic mood disorder consisting of a cluster of depressive subtypes existing in a relatively homogeneous symptomatic clinical continuum, extending from subsyndromal depressive sympt...
journal_title:Journal of affective disorders
pub_type:
doi:10.1016/s0165-0327(97)00064-5
更新日期:1997-08-01 00:00:00